History of Kyowa KirinLearn more about our heritage and
contributions to healthcare

Kyowa Kirin is a pharmaceutical company,
formed from a combination of the depth of
and strong business record of
Kyowa Hakko Kogyo and Kirin Pharma.

Find out the combined histories of Kyowa
Hakko Kogyo and Kirin Pharma, followed by the history
of Kyowa Kirin,
touching upon their
performance in the field of research and
lol下注 development to date.


Establishment of Kirin Brewery Co., Ltd.

Kirin Brewery Co., Ltd.


Establishment of Kyowa Hakko Kogyo Co., Ltd. as a secondary company of Kyowa Sangyo Co., Ltd, as part of industrial readjustment plans.

Kyowa Hakko Kogyo Co., Ltd.


Introduced production technology of Streptomycin, an anti-tubercular drug, from US pharmaceutical company Merck & Co., Inc. and succeeded in its mass production. Contributed to the wiping out of tuberculosis in Japan (beginning of involvement in pharmaceutical business operations).

Lapping bus for commerce of Streptomycin


lol下注Success of isolation and commercially mass-production of the anticancer drug, Mitomycin C.

lol下注Invention of the process of L-glutamic acid production by fermentation (a world first).


lol下注Initiation of full-scale involvement in the pharmaceutical business.

Release of Mitomycin C, an anticancer drug, and Spiramycin, an antibiotic drug.


lol下注Release of 5-FU, an anticancer drug.


lol下注Release of Leunase, an anticancer drug.


The Research Institute for Production Development foundation begins full-scale research towards the commercialization of erythropoietin.


Supported the establishment in the U.S.A. of the La Jolla Institute for Allergy and Immunology (LIAI).

La Jolla Institute


elease of ESPO®, an erythropoietin (EPO) drug.


Release of GRAN®, G-CSF drug.

Release of Coniel, a remedy for hypertension and agina pectoris.


Establishment of BioWa, Inc. in the United States to promote Kyowa Hakko's therapeutic antibody business.


lol下注The launch of Kirin Pharma Company, Limited to accompany the adoption by Kirin Brewery Company, Limited of a pure holding company system. Release of NESP®, a long-acting erythropoietic stimulating drug.

Established COMPLEGENT®, a novel antibody engineering technology that enhances the efficacy of antibodies, and licensed to BioWa, Inc, its subsidiary.

Capital alliance between Kyowa Hakko Group and Kirin Group.


Release of REGPARA®, a drug for secondary hyperparathyroidism.

lol下注Spun off its biochemical business, establishing Kyowa Hakko Bio Co., Ltd.

lol下注Kyowa Hakko Kirin was formed through the merger of Kyowa Hakko Kogyo and Kirin Pharma.


lol下注Introduced "Commitment to Life".


Acquired ProStrakan Group plc.


Launch of Poteligeo® in Japan, a Therapeutic Antibody for Adult T-cell Leukemia-Lymphoma (ATL)


Launch of NOURIAST® tablets 20 mg in Japan, a novel antiparkinsonian agent.


lol下注ProStrakan Completes Acquisition of Archimedes.

Launch of Sustained-Duration G-CSF Product G-LASTA® in Japan.


lol下注Rebranding Western Pharmaceutical Subsidiaries to "Kyowa Kirin".

lol下注Launch of LUMICEF® for Psoriasis Treatment in Japan.


lol下注Crysvita® approved in the US and Europe, sales to start as a treatment for patients with X-linked hypophosphatemia.

Poteligeo® approved in the US and Europe as a treatment for mycosis fungoides (MF) and Sézary syndrome (SS).


Trade name changed to current "Kyowa Kirin Co., Ltd." from Kyowa Hakko Kirin Co., Ltd.

lol下注Crysvita® launched in Japan for the treatment of FGF23-related Hypophosphatemic Rickets and Osteomalacia.

lol下注Nourianz™ launched in the US for use in Parkinson's disease.

CI logo of Kyowa Kirin